FIG 7.

Long-chain acylcarnitines elevated in CPT2^B−/− mouse hippocampus and cortex are contained within the CNS and not delivered from the brain into the blood. Abundances of acylcarnitines were determined from dried blood spots collected from common carotid arteries and external jugular veins from CPT2^lox/lox and CPT2^B−/− mice fasted for 4 h immediately prior to blood collection (n = 5). Abundances of individual acylcarnitine species in arterial and venous blood from 4-h-fasted adult mice are shown. The data are expressed as means and SEM. The data were analyzed using repeated-measures two-way analysis of variance with Sidak tests for multiple comparisons. *, α = 0.05; **, α = 0.01; ns, not significant.