Table 3. Multivariate analysis of predictors associated with disease-specific mortality and overall mortality.
Predictors | Disease-specific mortality | Overall mortality | ||
---|---|---|---|---|
p-value | HR (95% CI) | p-value | HR (95% CI) | |
Age at diagnosis (continuous) | 0.72 | 1.01 (0.95–1.08) | <0.01 | 1.07 (1.04–1.11) |
Preoperative PSA (continuous) | 0.80 | 1.00 (0.97–1.03) | 0.67 | 1.00 (0.98–1.01) |
Pathologic Gleason grade group | 0.05 | 1.44 (1.00–2.06) | 0.85 | 1.02 (0.86–1.20) |
Extraprostatic extension | 0.08 | 3.40 (0.86–13.35) | 0.06 | 1.54 (0.98–2.41) |
Seminal vesicle invasion | 0.02 | 3.82 (1.31–11.17) | <0.01 | 2.38 (1.42–4.00) |
Positive surgical margin | 0.46 | 1.48 (0.53–4.15) | 0.44 | 1.18 (0.78–1.79) |
Positive lymph nodes | 0.13 | 2.50 (0.77–8.05) | 0.64 | 0.78 (0.28–2.18) |
HR, hazard ratio; CI, confidence interval; PSA, prostate-specific antigen.