Table 4.
Baseline BCVA | P value | BCVA improvement at 12month | P value | Adjusted p value | ||
---|---|---|---|---|---|---|
ARMS2 A69S (rs10490924) | TT | 0.42 ± 0.37 | −0.12 ± 0.28 | |||
TG | 0.49 ± 0.40 | −0.20 ± 0.33 | ||||
GG | 0.30 ± 0.24 | 0.48 | −0.14 ± 0.20 | 0.34 | NA | |
CFH I62V (rs800292) | GG | 0.41 ± 0.37 | −0.15 ± 0.26 | |||
GA | 0.43 ± 0.41 | −0.16 ± 0.32 | ||||
AA | 0.54 ± 0.45 | 0.33 | −0.25 ± 0.43 | 0.39 | NA | |
CFH (rs1329428) | CC | 0.42 ± 0.37 | −0.17 ± 0.27 | |||
CT | 0.43 ± 0.38 | −0.15 ± 0.30 | ||||
TT | 0.40 ± 0.45 | 0.93 | −0.14 ± 0.33 | 0.48 | NA | |
C2-CFB-SKIV2L (rs429608) | AA | 0.70 ± 0.42 | −0.50 ± 0.14 | |||
AG | 0.49 ± 0.44 | −0.30 ± 0.37 | ||||
GG | 0.41 ± 0.36 | 0.12 | −0.13 ± 0.27 | 1.0 × 10−3 | 3.0 × 10−3(※) | |
C3 (rs2241394) | GG | 0.7 | −0.18 | |||
GC | 0.52 ± 0.39 | −0.18 ± 0.29 | ||||
CC | 0.41 ± 0.37 | 0.11 | −0.15 ± 0.29 | 0.70 | NA | |
CETP (rs3764261) | TT | 0.27 ± 0.09 | −0.04 ± 0.40 | |||
TG | 0.39 ± 0.34 | −0.18 ± 0.23 | ||||
GG | 0.45 ± 0.39 | 0.081 | −0.16 ± 0.30 | 0.42 | NA | |
ADAMTS9 (rs6795735) | CC | 0.33 ± 0.30 | −0.14 ± 0.28 | |||
CT | 0.35 ± 0.28 | −0.09 ± 0.26 | ||||
TT | 0.45 ± 0.39 | 0.083 | −0.18 ± 0.30 | 0.057 | NA |
(※)adjusting for age, gender, baseline BCVA, and AMD subtype.