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. 2020 Apr 28;10:7188. doi: 10.1038/s41598-020-64301-z

Table 4.

Visual improvement according to genotypes at 12-month.

Baseline BCVA P value BCVA improvement at 12month P value Adjusted p value
ARMS2 A69S (rs10490924) TT 0.42 ± 0.37 −0.12 ± 0.28
TG 0.49 ± 0.40 −0.20 ± 0.33
GG 0.30 ± 0.24 0.48 −0.14 ± 0.20 0.34 NA
CFH I62V (rs800292) GG 0.41 ± 0.37 −0.15 ± 0.26
GA 0.43 ± 0.41 −0.16 ± 0.32
AA 0.54 ± 0.45 0.33 −0.25 ± 0.43 0.39 NA
CFH (rs1329428) CC 0.42 ± 0.37 −0.17 ± 0.27
CT 0.43 ± 0.38 −0.15 ± 0.30
TT 0.40 ± 0.45 0.93 −0.14 ± 0.33 0.48 NA
C2-CFB-SKIV2L (rs429608) AA 0.70 ± 0.42 −0.50 ± 0.14
AG 0.49 ± 0.44 −0.30 ± 0.37
GG 0.41 ± 0.36 0.12 −0.13 ± 0.27 1.0 × 10−3 3.0 × 10−3(※)
C3 (rs2241394) GG 0.7 −0.18
GC 0.52 ± 0.39 −0.18 ± 0.29
CC 0.41 ± 0.37 0.11 −0.15 ± 0.29 0.70 NA
CETP (rs3764261) TT 0.27 ± 0.09 −0.04 ± 0.40
TG 0.39 ± 0.34 −0.18 ± 0.23
GG 0.45 ± 0.39 0.081 −0.16 ± 0.30 0.42 NA
ADAMTS9 (rs6795735) CC 0.33 ± 0.30 −0.14 ± 0.28
CT 0.35 ± 0.28 −0.09 ± 0.26
TT 0.45 ± 0.39 0.083 −0.18 ± 0.30 0.057 NA

(※)adjusting for age, gender, baseline BCVA, and AMD subtype.