Figure 2.

Multivariate regression analysis: variables that are predictors of progression to secondary progressive multiple sclerosis. Disease activity is Physician-reported multiple sclerosis disease activity based on the physician’s overall perception of the patient’s disease activity, ranging from “no activity to high activity” (no specific definition of disease activity was provided to the physicians); an odds ratio >1 implies a higher risk of secondary progressive multiple sclerosis; the blue box highlights the significant predictors. EDSS: Expanded Disability Status Scale; MRI: magnetic resonance imaging; MS: multiple sclerosis; PRF: patient record form; SPMS: secondary progressive multiple sclerosis; T2: transverse relaxation time. Black dots indicate odds ratio (point estimate); black line indicates the 95% confidence interval.