Table 2.

PANTHER Protein Classes Most Represented in CFs pre-treated with 1 μM PTC-209 (pValue and FDR < 0.05).

PANTHER Protein Class	PANTHER ID	Type of regulation (+/−)	pValue	FDR
oxidoreductase	PC00176	+	0.000044	0.00315
methyltransferase	PC00155	+	0.0000805	0.0173
aminoacyl-tRNA synthetase	PC00047	+	0.000087	0.00932
oxidase	PC00175	+	0.000193	0.00831
cytoskeletal protein	PC00085	−	0.00000016	0.00000857
nucleic acid binding	PC00171	−	0.0000002	0.00000861
G-protein modulator	PC00022	−	0.000000241	0.00000865
defence/immunity protein	PC00090	−	0.000000454	0.0000122
enzyme modulator	PC00095	−	0.0000016	0.0000376
glycosyltransferase	PC00111	−	0.000024	0.000471
signalling molecule	PC00207	−	0.000609	0.00818
cytokine	PC00083	−	0.00075	0.00896
microtubule family cytoskeletal protein	PC00157	−	0.00137	0.0128
chemokine	PC00074	−	0.0019	0.0141
receptor	PC00197	−	0.00235	0.0168
extracellular matrix protein	PC00102	−	0.00611	0.0398