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. 2018 Apr 6;16(1):59–70. doi: 10.1093/ons/opy034

TABLE 3.

Summary of Preoperative and Postoperative MRI Status and Postresection NIR Fluorescence Status

Cavernous sinus invasion GTR (n) GTR (%) FRα-overexpressing Residual neoplasm predicted by NIR Clinically significant tumor
Knosp grade (n) adenomas (n) in FRα-overexpressing patients (%)a recurrenceb (%)
0 (2) 2 100 1 100 0
1 (5) 4 80 3 100 0
2 (3) 1 33 2 100 0
3 (2) 1 50 1 100 0
4 (2) 0 0 2 0 50%

FRα = folate receptor alpha; GTR = gross total resection; MRI = magnetic resonance imaging.

aPostoperative MRI from day 1, 2-mo, and 6- to 12-mo follow-up visits were used. If postoperative day 1 MRI was inconclusive regarding residual neoplasm, a later-date MRI was used.

bDefined as recurrence needing repeat treatment or causing new symptoms at 1-yr follow-up.