Table 1.
Characteristic | Datum | Percentage |
---|---|---|
Age, median (range), y | 58.1 (19.7-90.5) | |
Male:female ratio | 135:126 | |
Stage at diagnosis | ||
I/II/III/IV | 70/24/47/120 | 26.8/9.2/18.0/45.9 |
FLIPI | ||
Low/intermediate/high/missing data | 127/61/70/3 | 49.2/23.6/27.1* |
FLIPI-2 | ||
Low/intermediate/high/missing data | 20/34/25/182 | 25.3/43.0/31.6* |
Grade | ||
1,2/3A/unknown | 197/54/10 | 78.5/21.5* |
Treatment | ||
Rituximab-CHOP | 89 | 34.1 |
Radiation | 61 | 23.4 |
Rituximab-bendamustine | 29 | 11.1 |
Observation | 21 | 8.0 |
Rituximab | 16 | 6.1 |
Rituximab-CVP | 13 | 4.6 |
Radiation, R-CHOP | 4 | 1.5 |
Radiation, rituximab | 2 | 0.8 |
CHOP | 2 | 0.8 |
Rituximab-EPOCH | 2 | 0.8 |
Biaxin/chlorambucil | 1/1 | 0.4/0.4 |
Rituximab-CHEP/rituximab-CDOP/rituximab-GCVP/DA-EPOCH-rituximab | 1/1/1/1 | 0.4/0.4/0.4/0.4 |
Rituximab, IFN a/rituximab, fludarabine/rituximab, Cytoxan,† prednisone/rituximab, fludarabine, mitoxantrone, Decadron†/methotrexate | 1/1/1/1/1 | 0.4/0.4/0.4/0.4/0.4 |
Lost follow-up | 11 | 4.2 |
Interval between initial biopsy and treatment, median (range), mo | 2.1 (0-244.5) 11 missing | |
Follow-up duration of all patients, median (range), y | 5.9 (0-16.6) | |
Progression/death | 69/30 | 26.4/11.5 |
CDOP, cyclophosphamide, pegylated liposomal doxorubicin, vincristine, and prednisone; CHEP, cyclophosphamide, doxorubicin, etoposide, and prednisone; CHOP, cyclophosphamide, doxorubicin, vincristine, and prednisone; CVP, cyclophosphamide, vincristine, and prednisone; DA-EPOCH, dose-adjusted etoposide, prednisone, vincristine, cyclophosphamide, doxorubicin; GCVP, gemcitabine, cyclophosphamide, vincristine, and prednisolone; IFN, interferon; R-CHOP, rituximab with CHOP.
Percentages pertain to patients with available data.
Brand (generic): Cytoxan (cyclophosphamide); Decadron (dexamethasone).