Table 1.
Multivariate analysis of risk factors for bleeding
| Predictor | Purpura | Gingival bleeding | Epistaxis | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| Male | 0.67 (0.62-0.71) | <.001 | 1.06 (0.98-1.15) | .145 | 1.46 (1.33-1.60) | <.001 |
| ≥60 y of age | 1.27 (1.19-1.36) | <.001 | 0.98 (0.90-1.07) | .685 | 0.81 (0.74-0.90) | <.001 |
| Platelet count <10 × 109/L | 5.07 (4.69-5.48) | <.001 | 4.17 (3.81-4.57) | <.001 | 2.29 (2.05-2.55) | <.001 |
| Purpura | 3.22 (2.87-3.61) | <.001 | 1.34 (1.19-1.50) | <.001 | ||
| Gingival bleeding | 3.15 (2.80-3.53) | <.001 | 2.32 (2.10-2.56) | <.001 | ||
| Epistaxis | 1.28 (1.13-1.44) | <.001 | 2.37 (2.14-2.61) | <.001 | ||
| Hematuria | 2.05 (1.68-2.50) | <.001 | 2.36 (2.07-2.69) | <.001 | 1.61 (1.40-1.86) | <.001 |
| Melena | 1.04 (0.88-1.23) | .674 | 1.41 (1.23-1.62) | <.001 | 1.37 (1.17-1.59) | <.001 |
| ICH | 0.62 (0.44-0.86) | <.001 | 1.27 (0.92-1.74) | .144 | 1.21 (0.85-1.73) | .285 |
| Hematuria | Melena | ICH | ||||
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| Male | 1.17 (1.03-1.33) | .015 | 1.31 (1.16-1.48) | <.001 | 0.98 (0.74-1.28) | .858 |
| ≥60 y of age | 1.10 (0.96-1.26) | .179 | 2.63 (2.25-3.08) | <.001 | 3.09 (2.13-4.47) | <.001 |
| Platelet count <10 × 109/L | 2.93 (2.49-3.46) | <.001 | 4.15 (3.51-4.91) | <.001 | 2.96 (2.11-4.15) | <.001 |
| Purpura | 2.08 (1.71-2.53) | <.001 | 1.09 (0.92-1.28) | .342 | 0.63 (0.46-0.87) | .005 |
| Gingival bleeding | 2.36 (2.07-2.69) | <.001 | 1.40 (1.22-1.61) | <.001 | 1.27 (0.93-1.74) | .129 |
| Epistaxis | 1.66 (1.44-1.91) | <.001 | 1.38 (1.19-1.61) | <.001 | 1.22 (0.86-1.73) | .270 |
| Hematuria | 2.47 (2.09-2.91) | <.001 | 1.56 (1.04-2.35) | .033 | ||
| Melena | 2.44 (2.06-2.88) | <.001 | 0.99 (0.64-1.54) | .965 | ||
| ICH | 1.52 (1.00-2.30) | .048 | 0.97(0.62-1.52) | .896 | ||