Figure 5.

Highly activated transferred Tregs express high levels antiproliferative and apoptotic genes. (A) Network diagram of pathway terms from the Hallmark gene set⁴³ enriched in DE gene list up in activated-like transferred Tregs vs aTregs (top). Expression values of genes from pathways in panel A (top) in activated-like transferred Tregs and aTregs (bottom). (B) p53 target⁴⁹ gene-set scores by UMAP clusters from Figure 4B. (C) Top p53 target genes DE between activated-like transferred Tregs and aTregs manually annotated as antiproliferative, apoptotic, proliferative, antiapoptotic, or other.