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. 2020 Apr 24;4(8):1722–1736. doi: 10.1182/bloodadvances.2019000978

Figure 5.

Figure 5.

Gata2 heterozygous loss increases the incidence of EVI1-driven leukemia with high platelets and Mks. (A) PLT counts in the peripheral blood of leukemic 3q21q26-EVI1 (red circle) and 3q21q26-EVI1::Gata2+/gfp (blue square) mice. An orange dotted line represents PLT levels of age-matched WT mice. (B) Percentages of Mks in the bone marrows of leukemic 3q21q26-EVI1 (red circle) and 3q21q26-EVI1::Gata2+/gfp (blue square) mice. (C) Kaplan-Meier survival curves of 3q21q26-EVI1 (High-Mk type leukemia [orange dotted line], Low-Mk type leukemia [red line]), and 3q21q26-EVI1::Gata2+/gfp mice (High-Mk type leukemia [turquoise line] or Low-Mk type leukemia [blue dashed line]). *P < .05 (log-rank test).