Table 1.
Characteristics of 6442 adult patients with AML who received cytarabine-anthracycline-based IC
| Overall | Hospital IC volume | P | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Low | Medium | High | |||||||
| n | % | n | % | n | % | n | % | ||
| Total | 6442 | 2045 | 2239 | 2158 | |||||
| Sex | |||||||||
| Female | 2859 | 44.4 | 937 | 45.8 | 982 | 43.9 | 940 | 43.6 | .28 |
| Male | 3583 | 55.6 | 1108 | 54.2 | 1257 | 56.1 | 1218 | 56.4 | |
| Age, y | |||||||||
| Median (IQR) | 61 (50-68) | 61 (50-69) | 61 (50-68) | 60 (49-68) | |||||
| 18-39 | 798 | 12.4 | 243 | 11.9 | 279 | 12.5 | 276 | 12.8 | .52 |
| 40-59 | 2223 | 34.5 | 691 | 33.8 | 765 | 34.2 | 767 | 35.5 | |
| 60-89 | 3421 | 53.1 | 1111 | 54.3 | 1195 | 53.4 | 1115 | 51.7 | |
| Race/ethnicity | |||||||||
| Non-Hispanic white | 4669 | 72.5 | 1409 | 68.9 | 1723 | 77.0 | 1537 | 71.2 | <.01 |
| Non-Hispanic African American | 488 | 7.6 | 182 | 8.9 | 143 | 6.4 | 163 | 7.6 | |
| Hispanic | 418 | 6.5 | 155 | 7.6 | 124 | 5.5 | 139 | 6.4 | |
| Other | 818 | 12.7 | 286 | 14.0 | 239 | 10.7 | 293 | 13.6 | |
| Unknown | 49 | 0.8 | 13 | 0.6 | 10 | 0.4 | 26 | 1.2 | |
| Marital status | |||||||||
| Single | 2389 | 37.1 | 782 | 38.2 | 812 | 36.3 | 795 | 36.8 | .59 |
| Married | 3476 | 54.0 | 1090 | 53.3 | 1227 | 54.8 | 1159 | 53.7 | |
| Other | 577 | 9.0 | 173 | 8.5 | 200 | 8.9 | 204 | 9.5 | |
| Year of admission | |||||||||
| 2010 | 831 | 12.9 | 281 | 13.7 | 287 | 12.8 | 263 | 12.2 | <.01 |
| 2011 | 871 | 13.5 | 309 | 15.1 | 318 | 14.2 | 244 | 11.3 | |
| 2012 | 947 | 14.7 | 334 | 16.3 | 331 | 14.8 | 282 | 13.1 | |
| 2013 | 941 | 14.6 | 345 | 16.9 | 335 | 15.0 | 261 | 12.1 | |
| 2014 | 921 | 14.3 | 277 | 13.5 | 330 | 14.7 | 314 | 14.6 | |
| 2015 | 923 | 14.3 | 257 | 12.6 | 304 | 13.6 | 362 | 16.8 | |
| 2016 | 917 | 14.2 | 227 | 11.1 | 302 | 13.5 | 388 | 18.0 | |
| 2017 | 91 | 1.4 | 15 | 0.7 | 32 | 1.4 | 44 | 2.0 | |
| Readmission | |||||||||
| No | 1982 | 30.8 | 709 | 34.7 | 676 | 30.2 | 597 | 27.7 | <.01 |
| Yes | 4460 | 69.2 | 1336 | 65.3 | 1563 | 69.8 | 1561 | 72.3 | |
| Length of stay, d | |||||||||
| Range | 4-175 | 4-175 | 5-156 | 4-159 | |||||
| Median (IQR) | 29 (25-38) | 29 (24-37) | 29 (25-38) | 30 (25-39) | <.01 | ||||
| Discharge status | |||||||||
| Alive | 5414 | 84.0 | 1696 | 82.9 | 1863 | 83.2 | 1855 | 86.0 | .05 |
| Hospice | 238 | 3.7 | 76 | 3.7 | 89 | 4.0 | 73 | 3.4 | |
| Dead | 790 | 12.3 | 273 | 13.3 | 287 | 12.8 | 230 | 10.7 | |
| Transferred from other hospital | |||||||||
| No | 5450 | 84.6 | 1881 | 92.0 | 1884 | 84.1 | 1685 | 78.1 | <.01 |
| Yes | 992 | 15.4 | 164 | 8.0 | 355 | 15.9 | 473 | 21.9 | |
| Hospital location | |||||||||
| Rural | 283 | 4.4 | 187 | 9.1 | 8 | 0.4 | 88 | 4.1 | <.01 |
| Urban | 6159 | 95.6 | 1858 | 90.9 | 2231 | 99.6 | 2070 | 95.9 | |
| Teaching hospital | |||||||||
| No | 2622 | 40.7 | 1248 | 61.0 | 908 | 40.6 | 466 | 21.6 | <.01 |
| Yes | 3820 | 59.3 | 797 | 39.0 | 1331 | 59.4 | 1692 | 78.4 | |
| Hospital bed size | |||||||||
| 000-199 | 297 | 4.6 | 187 | 9.1 | 52 | 2.3 | 58 | 2.7 | <.01 |
| 200-299 | 673 | 10.4 | 417 | 20.4 | 103 | 4.6 | 153 | 7.1 | |
| 300-399 | 1093 | 17.0 | 559 | 27.3 | 368 | 16.4 | 166 | 7.7 | |
| 400-499 | 801 | 12.4 | 370 | 18.1 | 431 | 19.2 | 0 | 0.0 | |
| 500+ | 3578 | 55.5 | 512 | 25.0 | 1285 | 57.4 | 1781 | 82.5 | |
| Hospital region | |||||||||
| South | 3109 | 48.3 | 987 | 48.3 | 917 | 41.0 | 1205 | 55.8 | <.01 |
| Northeast | 863 | 13.4 | 149 | 7.3 | 298 | 13.3 | 416 | 19.3 | |
| Midwest | 1151 | 17.9 | 403 | 19.7 | 411 | 18.4 | 337 | 15.6 | |
| West | 1319 | 20.5 | 506 | 24.7 | 613 | 27.4 | 200 | 9.3 | |