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The protein-protein interaction (PPI) network analysis: (a) PPI network of differentially expressed genes: (b) submodule 1; (c) submodule 2; (d) submodule 3. The submodules in the PPI network were extracted by MCODE based on PPI score > 3. The rosy red circular nodes denote upregulated genes. The green circular nodes represent significantly downregulated genes. The node size represents degree.
