Table 1.
Patient demographic and clinical characteristics (physician reported)
| Characteristic | TIRs (n = 483) |
TRs (n = 930) |
All (n = 1413) |
p-valuea |
|---|---|---|---|---|
| Mean age, years (±SD) | 42.6 (±13.1) | 40.5 (±12.8) | 41.2 (±13.0) | 0.003 |
| Female, n (%) | 368 (76.2) | 649 (69.8) | 1017 (72.0) | 0.011 |
| Country | 0.004 | |||
| France | 85 (17.6) | 110 (11.8) | 195 (13.8) | |
| Germany | 93 (19.3) | 189 (20.3) | 282 (20.0) | |
| Italy | 46 (9.5) | 71 (7.6) | 117 (8.3) | |
| Spain | 61 (12.6) | 97 (10.4) | 158 (11.2) | |
| UK | 52 (10.8) | 103 (11.1) | 155 (11.0) | |
| USA | 146 (30.2) | 360 (38.7) | 506 (35.8) | |
| Treating physician specialityb | 0.061 | |||
| PCP/GP | 327 (67.7) | 674 (72.5) | 1001 (70.8) | |
| Neurologist | 156 (32.3) | 256 (27.5) | 412 (29.2) | |
| Concomitant conditions, n (%) | ||||
| Anxiety | 145 (30.0) | 167 (18.0) | 312 (22.1) | < 0.001 |
| Stress | 83 (17.2) | 113 (12.2) | 196 (13.9) | 0.009 |
| Depression | 95 (19.7) | 85 (9.1) | 180 (12.7) | < 0.001 |
| Sleeping disorder, n (%) | 40 (8.3) | 36 (3.9) | 76 (5.4) | < 0.001 |
| Current cardiovascular risk, n (%)c | < 0.001 | |||
| Mild | 364 (80.0) | 757 (87.3) | 1121 (84.8) | |
| Moderate | 81 (17.8) | 103 (11.9) | 184 (13.9) | |
| Severe | 10 (2.2) | 7 (0.8) | 17 (1.3) | |
| Cardiovascular risk at start of acute migraine medication, n (%)c | 0.003 | |||
| Mild | 355 (80.7) | 727 (87.5) | 1082 (85.1) | |
| Moderate | 71 (16.1) | 92 (11.1) | 163 (12.8) | |
| Severe | 14 (3.2) | 12 (1.4) | 26 (2.0) | |
| Current cardiovascular condition, n (%) | 109 (22.6) | 142 (15.3) | 251 (17.8) | < 0.001 |
| Past cardiovascular condition, n (%) | 106 (21.9) | 125 (13.4) | 231 (16.3) | < 0.001 |
| Employment characteristics | ||||
| Currently employed, n (%) | 318 (68.7) | 633 (69.6) | 951 (69.3) | 0.739 |
| Mean No. of hours worked/per week (SD) | 36.6 (9.5) | 36.6 (9.6) | 36.6 (9.6) | 0.951 |
| Mean No. of work days missed because of doctors’ appointments, (±SD)d | 1.09 (±1.88) | 0.60 (±2.28) | 0.76 (±2.17) | < 0.001 |
| Mean No. of work days missed because of migraine, (±SD)d | 2.12 (±3.81) | 0.89 (±2.43) | 1.29 (±3.01) | < 0.001 |
aP-values from test of two group difference: t-test for continuous variables and chi-square for categorical variables. bPhysician currently managing the patient. cSubjective opinion of the physician.dDuring the past 3 months
SD = standard deviation; TIR = triptan insufficient responder; TR = triptan responder