Table 1.
HLA typing of donor groups with fully mismatched HLA locus used in experiments
| Individual | HLA locus | ||||||
|---|---|---|---|---|---|---|---|
| HLA-A | HLA-B | HLA-DR, | |||||
| Group 1 | A | 26 (10) | 68 (28) | 60 (40) | 52 (5) | 07 | 07 |
| B | 11 | 33 (19) | 54 (22) | 58 (17) | 04 | 14 (6) | |
| I | 2 | 24 (9) | 62 (15) | 46 | 12 (5) | 16 (2) | |
| Group 2 | A | 02 | 24 (9) | 62 (15) | 46 | 12 (5) | 16 (2) |
| B | 11 | 33 (19) | 54 (22) | 58 (17) | 04 | 14 (6) | |
| I | 24 (9) | 31 (19) | 35 | 61 (40) | 11 (5) | 15 (2) | |
| Group 3 | A | 11 | 33 (19) | 62 (15) | 58 (17) | 17 (3) | 4 |
| B | 02 | 11 | 75 (15) | 46 | 08 | 15 (2) | |
| I | 03 | 31 (19) | 46 | 51 (5) | 04 | 09 | |
The HLA typing of different individuals (Numbers represent serological antigens of HLA locus) are showed. Each group include individual A (for A-CD8+ T cells and A-CD4+ T cells), individual B (for B-APCs) and individual I (for I-APCs), The HLA-A, -B and -DR antigens of individual A, individual B and individual I in the same group are completely mismatched between each other. (Each group of donors whose HLA-A, -B and -DR fully mismatched with each other were selected from over 130 volunteers for independent experiments