Fig. 3.

Amount of positive cases for lesions detected with pTDP-43^409/410, pTDP-43⁴⁰⁹, pTDP-43^403/404, C- and N-t-TDP-43 in (a, d) dentate gyrus, (b, e) CA1 and (c, f) temporal cortex, according to a neuropathological classification (non-AD, p-preAD, AD^TDP-, AD^{TDP + CTF}, AD^TDP + FL and FTLD-TDP) (a-c), or further grouped by clinical diagnosis (non-demented – including neuropathological non-AD and p-preAD cases, sympAD – all cases with an exclusive AD clinical presentation, AD/FTD – cases with signs of AD as well as FTD symptoms, and FTD – cases with an exclusive FTD clinical presentation) (d-f). Non-parametric, Friedman test for related samples with Bonferroni correction for multiple testing was used to compare the amount of positive cases with each TDP-43 antibody within each clinical group. Each group was analyzed separately, *p < 0.05, **p < 0.01