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. 2020 Apr 29;8:61. doi: 10.1186/s40478-020-00934-5

Fig. 6.

Fig. 6

LATE-NC in non-AD, p-preAD, ADTDP-, ADTDP + CTF and ADTDP + FL cases. Most non-AD cases have no LATE-NC. ADTDP- have no LATE-NC. The majority of p-preAD and ADTDP + CTF cases present LATE-NC restricted to the medial temporal lobe (stage 2). One ADTDP + CTF case was not considered for the LATE-NC classification due to being considerably younger, despite presenting TDP-43 pathology. On the other hand, nearly half of ADTDP + FL cases have LATE-NC stage 2 and the remaining cases present more widespread LATE-NC, extended to the frontal cortex (stage 3)