Table 3.
Components | Downregulate | Upregulate | References |
---|---|---|---|
Paeoniflorin | TNF,IL6,PTGS2,CYP3A4,CASP3 | PPARG,CAT | [52–58] |
Albiflorin | TNF,IL6,PTGS2,CYP3A4,CASP3 | NOS3 | [52, 54, 57, 59] |
β-Sitosterol | IL6,PTGS2,TNF,CYP3A4,CASP3 | PPARG,CAT,NOS3 | [60–64] |
Mairin | PTGS2,TNF,CYP3A4,IL6,CASP3, | PPARG,CAT | [65–69] |
(+)-Catechin | TNF,PTGS2,CYP3A4,IL6,CASP3,JUN | PPARG,ESR1,TP53 | [70–76] |
Kaempferol | PTGS2,CYP3A4,TNF,IL6,CASP3,JUN | PPARG,CAT | [77–82] |
Gallic acid | PTGS2,CYP3A4,IL6,TNF,CASP3 | PPARG,CAT,NOS3 | [61, 83–87] |
Benzoylpaeoniflorin | PTGS2,IL6,TNF | [53, 84] |