Fig. 7.
miR-5106 accelerates fracture healing in vivo. a X-rays comparison of fracture healing between control, M2D-Exos, and M2D-ExosantagomiR−5106 groups on day 3, 7, 14 and 21 post-injury; b micro-CT three dimensional construction and cross sections of the fracture site among the three groups on day 14 and 21; c miR-5106 level in callus was measured by qRT-PCR analysis, n = 6 mice/group; d The H&E/Alcian-blue staining images on day 21 post-operation. e The statistical results of H&E/Alcian-blue staining; f BV and TV of the callus, BV/TV, and BMD datas on days 14 and 21 post-operation were assessed via micro-CT. n = 6 mice/group. Data are mean ± SD of triplicate experiments. *p < 0.05, **p < 0.01, ***p < 0.001