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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Mod Pathol. 2019 Apr 17;32(9):1344–1358. doi: 10.1038/s41379-019-0269-x

Figure 2: Histopathology, Fluorescence In Situ Hybridization and Immunohistochemistry (Case 1 & 4).

Figure 2:

Representative H&E-stained images of 9p24.1-amplified sarcomatoid renal cell carcinomas ((a) Case 4, 2.7-fold amplification by MSK-IMPACT, × 400 magnification; (d) Case 1, 3.5-fold amplification by MSK-IMPACT, × 200 magnification), corresponding fluorescence in situ hybridization ((b) Red: PD-L1, Green: PD-L2, Aqua: Centromere; (e) Orange: JAK2, Green: INSL6, Red: Centromere) and immunohistochemistry ((c) PD-L1, × 400 magnification; (f) phospho-STAT3, × 200 magnification) have been depicted. MSK-IMPACT, Memorial Sloan Kettering Cancer Center Integrated Mutation Profiling of Actionable Cancer Targets.