Table 2.
Significant plasma proteins for incident mobility disability in protein‐specific Cox proportional hazard risk model
| Gene symbol | Entre GeneID | Target | Model | ||||
|---|---|---|---|---|---|---|---|
| HR | 95%CI | Raw | FDR | ||||
| p‐value | q‐value | ||||||
| CTSS | 1520 | Cathepsin S | 1.33 | 1.17 | 1.51 | <.0001 | 0.007 |
| GDF15 | 7058 | MIC−1 | 1.45 | 1.23 | 1.72 | <.0001 | 0.007 |
| THBS2 | 9518 | TSP2 | 1.44 | 1.22 | 1.69 | <.0001 | 0.007 |
Model was adjusted for sex, baseline age, baseline BMI, education level, baseline smoking status, baseline physical activity, baseline MMSE, baseline CED‐S, and baseline gait speed.