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. 2014 Feb 26;38(5):865–891. doi: 10.1111/1574-6976.12067

Figure 6.

Figure 6

Domain organisation of transposases of the DDE family. The relative positions of the potential ZF, HTH, LZ and the ‘DDEK/R’ catalytic motif are indicated from left to right as light blue boxes. The figure illustrates the N‐terminal and C‐terminal extension of the different transposase examples. (a) Classical IS 1 with frameshift. The position of the frameshift window which is used to generate InsAB is indicated. (b) IS 1 without frameshift and the ISM hu11 group showing the deletion of the ZF, the C‐terminal extension and the increased spacing between the second (d) and (e) residues. (c) The IS 1595 family showing the classical IS 1595 group and the IS 1016 group which does not carry the N‐terminal ZF. (d) The IS 3 family including members with and without the translational frameshift. (e) The closely related IS 481 family which lack the N‐terminal HTH domain and exhibit an additional C‐terminal domain.