Table 1.

Personal and clinical characteristics of patients with severe acute respiratory syndrome coronavirus 2 infection by severity of disease

Characteristics	Total (n=96)	Disease severity		P value
		Mild (n=22)	Severe (n=74)
Median (interquartile range) age (years)	55 (44.3-64.8)	47.5 (36.8-56.3)	57 (47.5-66)	0.01
Men	58 (60)	9 (41)	49 (66)	0.03
Infected in Wuhan	28 (29)	2 (9)	26 (35)	0.01
Underlying diseases:
Hypertension	35 (36)	4 (18)	31 (42)	0.04
Diabetes mellitus	11 (11)	1 (5)	10 (14)	0.44
Heart disease	7 (7)	0 (0)	7 (9)	0.30
Lung disease	4 (4)	0 (0)	4 (5)	0.57
Liver disease	3 (3)	1 (5)	2 (3)	0.55
Renal disease	1 (1)	0 (0)	1 (1)	1.00
Malignancy	1 (1)	0 (0)	1 (1)	1.00
Immune compromise	1 (1)	0 (0)	1 (1)	1.00
Symptoms:
Fever	85 (89)	17 (77)	68 (92)	0.13
Cough	54 (56)	12 (55)	42 (57)	0.85
Sputum	26 (27)	7 (32)	19 (26)	0.59
Chest distress	12 (13)	2 (9)	10 (14)	0.85
Dizziness	7 (7)	0 (0)	7 (9)	0.30
Headache	4 (4)	0 (0)	4 (5)	0.57
Nausea	5 (5)	2 (9)	3 (4)	0.32
Vomiting	2 (2)	0 (0)	2 (3)	1.00
Diarrhoea	10 (10)	0 (0)	10 (14)	0.15
Myalgia	19 (20)	6 (27)	13 (18)	0.49
Fatigue	9 (9)	1 (5)	8 (11)	0.64
Treatment:
Gammaglobulin	53 (55)	4 (18)	49 (66)	<0.001
Glucocorticoids	78 (81)	9 (41)	69 (93)	<0.001
Antibiotics	33 (34)	1 (5)	32 (43)	0.001
Antivirals	96 (100)	22 (100)	74 (100)	NC
Time from illness onset to antiviral treatment (days):
≤5	63 (66)	14 (64)	49 (66)	0.82
>5	29 (30)	8 (36)	21 (28)	0.58
Disease severity/support:
Bilateral pulmonary infiltrates	80 (83)	12 (55)	68 (92)	<0.001
Invasive mechanical ventilation	10 (10)	0 (0)	10 (14)	0.15
ECMO	5 (5)	0 (0)	5 (7)	0.59
Intensive care unit admission	30 (31)	0 (0)	30 (41)	<0.001

ECMO=extracorporeal membrane oxygenation; NC=not calculable.