Table 2.
Detection of severe acute respiratory syndrome coronavirus 2 in patients with mild or severe disease at different stages after symptom onset in different sample types. Values are numbers affected/number tested (%) unless stated otherwise
| Sample types | After admission | Weeks since onset of symptoms | P values | |||
|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |||
| All patients: | ||||||
| Respiratory | 96/96 (100) | 42/44 (95) | 74/90 (82) | 64/89 (72) | 31/57 (54) | <0.001 |
| Stool | 55/93 (59) | 9/23 (39) | 28/59 (47) | 32/71 (45) | 20/57 (35) | 0.54 |
| Serum | 39/95 (41) | 5/36 (14) | 20/85 (23) | 19/85 (22) | 5/55 (9) | 0.12 |
| Urine | 1/67 (1) | 0/15 (0) | 1/53 (2) | 0/21 (0) | 0/19 (0) | NC |
| Mild disease: | ||||||
| Respiratory | 22/22 (100) | 11/12 (92) | 15/21 (71) | 9/19 (47) | 4/9 (44) | 0.04 |
| Stool | 13/22 (59) | 2/7 (29) | 8/16 (50) | 10/17 (59) | 5/9 (56) | 0.62 |
| Serum | 6/22 (27) | 0/9 (0) | 3/19 (16) | 2/17 (12) | 0/8 (0) | 0.67 |
| Urine | 0/19 (0) | 0/3 (0) | 0/15 (0) | 0/7 (0) | 0/3 (0) | NC |
| Severe disease: | ||||||
| Respiratory | 74/74 (100) | 31/32 (97) | 59/69 (86) | 55/70 (79) | 27/48 (56) | <0.001 |
| Stool | 42/71 (59) | 7/16 (44) | 20/43 (47) | 22/54 (41) | 15/48 (31) | 0.49 |
| Serum | 33/73 (45) | 5/27 (19) | 17/66 (26) | 17/68 (25) | 5/47 (11) | 0.20 |
| Urine | 1/48 (2) | 0/12 (0) | 1/38 (3) | 0/14 (0) | 0/16 (0) | NC |
NC=not calculable.