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. 2020 Apr 29;15(4):e0232138. doi: 10.1371/journal.pone.0232138

Table 1. Summary of clinical and pathological data on the potentially malignant disorder (PMD) and oral squamous cell carcinoma (OSCC) cases included in this study.

PMDs OSCCs
Overall Female Male Overall Female Male
Number of cases 14 12 2 68 35 33
Average age (years) 70 73 50 69 72 65
Age (years) Range 34–84 51–84 34–67 29–91 35–91 29–88
< 30 0 0 0 1 0 1
30–50 1 0 1 8 3 5
50–70 5 4 1 26 14 12
70 + 8 8 33 18 15
Number of patients who have never drunk or smoked 6 6 0 31 24 7
Anatomical location Inner mucosa of lips 1 1 0 1 1 0
Mobile part of the tongue 11 9 2 25 12 13
Floor of the mouth 1 0 1
Gum 1 1 0 26 16 10
Cheek mucosa 1 1 0 7 2 5
Intermaxillary region 4 1 3
Hard palate of the mouth 3 2 1
Soft palate of the mouth 1 1 0
Hyperplasia 3 3 0 Not applicable
Dysplasia Grade I 4 3 1
Dysplasia Grade II 2 2 0
Dysplasia Grade III 1 1 0
In situ Carcinoma 6 5 1
Cellular differentiation Well Not applicable 38 17 21
Medium 24 14 10
Poor 5 3 2
Keratinization Yes Not applicable 47 23 24
No 9 8 1
Not Determined 12 5 7
Perineural invasion Yes Not applicable 26 14 12
No 38 18 20
Not applicable 4
Vascular embolus Yes Not applicable 13 9 4
No 55 23 29
Not applicable 3