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. 2020 Apr 29;15(4):e0231762. doi: 10.1371/journal.pone.0231762

Fig 5. Caspase assay and caspase Western blot reveal apoptosis in canine OSA cell lines treated with vismodegib.

Fig 5

Increased cleaved caspase 3 & 7 protein expression was detected with vismodegib treatments at the respectively determined IC50 value in Abrams and D-17 canine OSA cell lines when compared to vehicle control (DMSO) treatment in both (A) colorimetric caspase 3/7 assay and (B) Western blot. * p < 0.05.