Table 1. Fixed Effects Model (FEL) results for sites with human-specific amino acid substitutions.

α, synonymous substitution rate. β, non-synonymous substitution rate. ω, d_N/d_S ratio. α = β, rate estimate under the neutral model. LRT, likelihood ratio test statistic for α = β versus α < β. Branch length, the total length of branches contributing to the inference at this site (used to scale d_N and d_S).

Site	α	β	ω	α = β	LRT	P-value	Branch length
159	1.42	0.63	0.44	0.85	2.80	0.10	7.37
172	0.86	0.66	0.77	0.72	0.24	0.62	6.18
192	0.27	0.38	1.40	0.35	0.17	0.68	3.02
201	0.54	0.30	0.56	0.38	0.69	0.41	3.21
216	5.15	0.21	0.04	0.63	12.36	0.00	13.97
347	2.76	0.25	0.09	0.86	16.41	0.00	8.33
430	1.24	0.41	0.33	0.64	3.11	0.08	5.58
662	0.14	0.43	3.08	0.35	1.40	0.24	2.98