Table 2. Single-Likelihood Ancestor Counting (SLAC) results for sites with human-specific amino acid substitutions.
ES, expected synonymous sites. EN, expected non-synonymous sites. S, inferred synonymous substitutions. N, inferred non-synonymous substitutions. P[S], expected proportion of synonymous sites. dS, inferred synonymous substitution rate. dN, inferred non-synonymous substitution rate. P [dN/dS > 1], binomial probability that S is no greater than the observed value, with Ps probability of success. P (dN/dS < 1), binomial probability that S is no less than the observed value, with Ps probability of success. Total branch length, the total length of branches contributing to the inference at this site (used to scale dN and dS).
| Site | ES | EN | S | N | P[S] | dS | dN | dN/dS | P [dN/dS > 1] | P [dN/dS < 1] | Total branch length |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 159 | 0.97 | 1.99 | 9 | 10 | 0.33 | 9.29 | 5.01 | 0.54 | 0.94 | 0.13 | 3.71 |
| 172 | 0.95 | 1.92 | 6 | 10 | 0.33 | 6.31 | 5.21 | 0.83 | 0.74 | 0.45 | 3.85 |
| 192 | 0.95 | 1.97 | 2 | 6 | 0.33 | 2.10 | 3.04 | 1.45 | 0.49 | 0.79 | 3.76 |
| 201 | 0.98 | 1.94 | 4 | 5 | 0.33 | 4.10 | 2.57 | 0.63 | 0.85 | 0.35 | 3.76 |
| 216 | 1.00 | 2.00 | 4 | 2 | 0.33 | 3.99 | 1.00 | 0.25 | 0.98 | 0.10 | 3.67 |
| 347 | 0.87 | 1.68 | 11 | 3 | 0.34 | 12.60 | 1.79 | 0.14 | 1.00 | 0.00 | 3.59 |
| 430 | 0.90 | 1.84 | 6 | 5 | 0.33 | 6.64 | 2.71 | 0.41 | 0.96 | 0.12 | 3.46 |
| 662 | 0.79 | 2.22 | 1 | 8 | 0.26 | 1.27 | 3.60 | 2.83 | 0.27 | 0.93 | 3.88 |