Table 3.
Species, sensitivity of Candida isolated, and mortality in solid organ transplant (SOT) patients separated by the use of antifungal prophylaxis at time of diagnosis
| Antifungal prophylaxis number (%) | No prophylaxis number (%) | P‐value | |
|---|---|---|---|
| SOT patients with candidemia | 12 (50) | 12 (50) | NS |
| Candida species | |||
| C. albicans | 6 (50) | 5 (42) | NS |
| C. glabrata | 3 (25) | 2 (17) | NS |
| C. parapsilosis | 1 (8) | 2 (17) | NS |
| C. krusei | 1 (8) | 0 | NS |
| C. dubliniensis | 0 | 1 (8) | NS |
| C. tropicalis | 1 (8) | 1 (8) | NS |
| Other | 0 | 1 (8) | NS |
| Fluconazole sensitivity of Candida species | |||
| Sensitive 1 | 8 (67) | 10 (83) | NS |
| SDD or resistant 2 | 4 (33) | 2 (17) | NS |
| 30 day all‐cause mortality | 3 (25) 3 | 2 (17) 4 | NS |
1
All sensitive isolates MIC ≤1 μg/mL.
2
All C. glabrata isolates in both groups SDD; 1 resistant isolate C. krusei.
3
The deaths occurred in kidney (n=2) and liver (n=1) transplant recipients.
4
The deaths occurred in kidney (n=2) transplant recipients.
NS, non‐significant; MIC, minimum inhibitory concentration; SDD, sensitive dose dependent.