Table 3. Summary of selected CpGs with estimators and P-values for significant mediators.
| CpGs | Chromosome | Gene | P(Sobel) | P(Joint) | |
|---|---|---|---|---|---|
| cg21926276 | chr11 | H19 | 0.2229 | 1.266e-03 | 1.662e-06 |
| cg27042065 | chr12 | CDCA3 | 0.0880 | 1.071e-01 | 4.409e-02 |
| cg26387355 | chr12 | LOC338797 | 0.1388 | 1.449e-02 | 1.558e-03 |
| cg15292688 | chr18 | ZNF519 | -0.2301 | 4.844e-02 | 1.084e-02 |
| cg24200525 | chr12 | SBF1 | -0.1127 | 3.018e-02 | 5.535e-03 |
| cg07690349 | chr11 | MUC5B | -0.1403 | 1.217e-02 | 9.126e-04 |
*The CpGs are the DNA methylation sites. Chromosomes and Genes are where the CpGs locate. is the estimation of log-hazard indirect effect. P(Sobel) is the Sobel test p-values and P(Joint) is the joint test p-values, which are corrected by bonferroni’s method.