Table 3.
Association of Psychiatric Comorbidity Indicatorsa with Past 30-Day Use and Poly-Use of Cannabis Products
| Odds Ratio (95%CI) relative to no use of cannabis in any form (Reference)b | |||
|---|---|---|---|
| Single Product Use | Dual-Product Use | Poly-Product Use | |
| Past 30-day non-cannabis substance use (yes vs. no) | |||
| E-cigarettes with nicotine | 10.94 (9.26, 12.91) | 14.97 (12.51, 17.90) | 55.34 (44.46, 68.88) |
| Cigarettes | 18.49 (14.71, 23.23) | 35.36 (28.00, 44.66) | 85.44 (65.99, 110.62) |
| Alcohol | 10.60 (9.25, 12.15) | 19.05 (16.04, 22.62) | 33.05 (26.00, 42.02) |
| Prescription stimulants | 6.89 (4.49, 10.56) | 26.15 (18.47, 37.03) | 117.00 (83.62, 163.69) |
| Prescription opioids | 4.53 (3.25, 6.31) | 14.49 (10.96, 19.16) | 91.72 (69.19, 121.60) |
| Psychiatric symptoms and traits (continuous variables in SD units) | |||
| Conduct problems | 1.91 (1.80, 2.03) | 2.30 (2.16, 2.45) | 2.50 (2.34, 2.67) |
| ADHD inattentive symptoms | 1.19 (1.12, 1.27) | 1.13 (1.05, 1.22) | 1.46 (1.34, 1.58) |
| ADHD impulsivity symptoms | 1.28 (1.20, 1.36) | 1.19 (1.11, 1.28) | 1.55 (1.43, 1.68) |
| Negative urgency | 1.22 (1.14, 1.30) | 1.42 (1.32, 1.53) | 1.59 (1.45, 1.75) |
| Positive urgency | 1.29 (1.21, 1.38) | 1.38 (1.28, 1.48) | 1.63 (1.50, 1.77) |
| Lack of premeditation | 1.39 (1.31, 1.48) | 1.41 (1.31, 1.52) | 1.69 (1.55, 1.84) |
| Lack of perseverance | 1.29 (1.21, 1.38) | 1.31 (1.22, 1.42) | 1.43 (1.30, 1.57) |
| Sensation seeking | 1.19 (1.12, 1.28) | 1.24 (1.15, 1.35) | 1.17 (1.06, 1.29) |
| Anhedonia | 1.28 (1.21, 1.36) | 1.33 (1.24, 1.43) | 1.35 (1.25, 1.47) |
| Depressive symptoms | 1.25 (1.18, 1.33) | 1.36 (1.26, 1.45) | 1.33 (1.21, 1.45) |
a
See Methods for operational definition of each psychiatric comorbidity variable.
b
From multinomial logistic regression models regressing number of cannabis products used on psychiatric comorbidity indicators adjusting for gender, race/ethnicity, age, and socioeconomic status; separate models were tested for each respective comorbidity indicator.