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. 2020 Apr 29;6(18):eaaz8031. doi: 10.1126/sciadv.aaz8031

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Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 3 — (A) CIA1 and CIA2 reduced cell growth of prostate cancer cells. Cell viability was measured 96 hours after CIA1 or CIA2 treatment. n = 3 per group. (B) CIA1 and CIA2 reduced colony formation ability of prostate cancer cells. PC3 cells were treated with inhibitor for 12 days. n = 3 per group. Two-way analysis of variance (ANOVA). (C) CIA1 and CIA2 reduced prostate cancer cell invasion. PC3 cells were treated with 1 μM CIA1 or CIA2 for 48 hours. Invasion was measured by transwell assay. n = 3 per group. One-way ANOVA. DMSO, dimethyl sulfoxide. (D) Angiogenesis was measured by human umbilical cord endothelial cell sprouting assay. n = 3 per group. One-way ANOVA. ***P < 0.001.