Table 2.
BEAM (N = 667) | R-BEAM (N = 195) | ||||
---|---|---|---|---|---|
Outcomes | N Eval | Prob (95% CI) | N Eval | Prob (95% CI) | p-value |
Neutrophil recovery | 665 | 193 | 0.18 | ||
30-day | 99 (98–100)% | 98 (96–100)% | 0.50 | ||
Platelet recovery | 663 | 192 | 0.72 | ||
100-day | 97 (96–98)% | 97 (94–99)% | 0.91 | ||
Non-relapse mortality | 667 | 195 | 0.12 | ||
1-year | 5 (3–6)% | 6 (3–10)% | 0.44 | ||
4-year | 9 (7–11)% | 11 (7–16)% | 0.39 | ||
Relapse/progression | 667 | 195 | 0.25 | ||
1-year | 31 (28–35)% | 28 (22–35)% | 0.41 | ||
4-year | 44 (40–48)% | 41 (33–48)% | 0.40 | ||
Progression-free survival | 667 | 195 | 0.75 | ||
1-year | 64 (60–68)% | 65 (59–72)% | 0.69 | ||
4-year | 47 (43–51)% | 48 (41–56)% | 0.77 | ||
Overall survival | 667 | 195 | 0.77 | ||
1-year | 78 (74–81)% | 81 (75–86)% | 0.33 | ||
4-year | 61 (57–65)% | 58 (51–65)% | 0.54 |
Abbreviations: BEAM: carmustine, etoposide, cytarabine and melphalan; R-BEAM: rituximab +BEAM; N Eval: number evaluated; Prob: probability; HCT: hematopoietic cell transplantation; DLBCL: diffuse large B cell lymphoma