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A) Initial phase of the exantematous rash. Merely teleangectatic blood vessels (arrows) B) Exanthematous rash biopsied three days after the onset. A small nest of Langerhans cell within the epidermis (arrow). Mild perivascular lymphocytic infiltration in the superficial dermis. C) A papulo-vesicular lesion. Spongiosis, a large intraepidermal nest of Langerhans cell. D) Maculo-papular exanthema. E) Haemorragic diffuse exanthematous rash. A small thrombus in a capillary vessel (arrow).
