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. 2019 Dec 4;33(5):905–915. doi: 10.1038/s41379-019-0418-2

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© The Author(s), under exclusive licence to United States & Canadian Academy of Pathology 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Nuclear and cytoplasmic protein levels of mitotic checkpoint protein BUB3, cyclin B1 (CCNB1) and pituitary tumor-transforming 1 (PTTG1) was scored by assessing the whole tumor area. The tiles represent examples of (a) nuclear BUB3, (b) cytoplasmic and nuclear BUB3, (c) CCNB1, and (e) PTTG1 protein levels. Cells identified by ImmunoPath as positive are marked in red for (d) CCNB1 and (f) PTTG1. Negative cells are apparent by the blue counterstain of the nuclei. Each tile is 500 µm × 500 µm.