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. 2020 Apr 29;10:7273. doi: 10.1038/s41598-020-64131-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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OCT retinal sections in control, P23H-1 and RCS rats. (A) Ocular fundus image from a P60 SD rat. The green arrow marks the location of the OCT retinal sections shown in (B–L). (B–F) OCT retinal sections encompassing the optic disc acquired from young (B) and old (C) SD control rats, and 30 (D), 210 (E) and 400 (F) days old P23H-1 rats. (G–L) OCT retinal sections encompassing the optic disc acquired from young (G) and old (H) PVG control rats, and 21 (I), 33 (J), 60 (K) and 300 (L) days old RCS rats. In the dystrophic strains is observed that the outer retina diminishes with age. Red arrows point to the position of the RPE. P: postnatal day.