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. 2020 Apr 29;10:7273. doi: 10.1038/s41598-020-64131-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Ocular fundus and BluePeak autofluorescence in control, P23H-1 and RCS rats. (A) Representative image from the ocular fundus of a young SD rat. (B–F) BluePeak autofluorescence signal acquired from young (B) and old (C) SD control rats, and 30 (D), 210 (E) and 400 (F) days old P23H-1 rats. (G-L) BluePeak autofluorescence signal acquired from young (G) and old (H) PVG control rats, and 21 (I), 33 (J), 60 (K) and 300 (L) days old RCS rats. Fundus autofluorescence represented by autofluorescent dots are seen from P210 onwards in the P23H-1 rat (E,F) and at P60 onwards in the RCS rat (K,L). P: postnatal day.