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. 2020 Feb 5;52(3):915–926. doi: 10.1007/s11250-019-02063-1

Table 3.

The significant results of logistic regression analysis within all SNP loci

SNP Model Genotype Tan Hu OR (95% CI) P value FDR_BH adjusted
SNP8 Codominant C/C 236 132 – – –
C/T 14 40 0.1958 (0.1027–0.3731) 7.16E−07a 1.00E+00
T/T 0 2 3.462e−10 (0-inf) 9.99E−01 1.00E+00
Dominant C/C 236 132 0.1864 (0.09818–0.354) 2.84E−07a 4.55E−06b
C/T-T/T 14 42
Recessive C/C-C/T 250 172 4.259e−10 (0-inf) 9.99E−01 1.00E+00
T/T 0 2
Additive – – – 0.1909 (0.1013–0.3599) 3.07E−07a 5.04E−06b
SNP9 Codominant T/T 236 132 – – –
T/A 14 39 0.2008 (0.1052–0.3834) 1.14E−06a 1.00E+00
A/A 0 3 3.462e−10 (0-inf) 9.99E−01 1.00E+00
Dominant T/T 236 132 0.1864 (0.09818–0.354) 2.84E−07a 4.55E−06b
T/A-A/A 14 42
Recessive T/T-T/A 250 171 4.234e−10 (0-inf) 9.99E−01 1.00E+00
A/A 0 3
Additive – – – 0.1931 (0.1028–0.3627) 3.15E−07a 5.04E−06b
SNP10 Codominant G/G 183 95 – – –
G/A 60 64 0.4867 (0.3164–0.7487) 1.05E−03a 1.01E−02b
A/A 7 15 0.2423 (0.09551–0.6145) 2.83E−03a 1.01E−02b
Dominant G/G 183 95 0.4403 (0.2924–0.6628) 8.50E−05a 6.43E−04b
G/A-A/A 67 79
Recessive G/G-G/A 243 159 0.3053 (0.1218–0.7656) 1.14E−02a 6.95E−02
A/A 7 15
Additive – – – 0.4892 (0.3483–0.687) 3.69E−05a 3.25E−04b
SNP12 Codominant C/C 134 62 – – –
C/T 96 85 0.5226 (0.3436–0.7948) 2.42E−03a 7.78E−03b
T/T 20 27 0.3427 (0.1786–0.6578) 1.28E−03a 7.78E−03b
Dominant C/C 134 62 0.4792 (0.322–0.7131) 2.87E−04a 8.35E−04b
C/T-T/T 116 112
Recessive C/C-C/T 230 147 0.4734 (0.2562–0.8749) 1.70E−02a 6.95E−02
T/T 20 27
Additive – – – 0.5645 (0.4201–0.7583) 1.47E−04a 4.27E−04b
SNP29 Codominant A/A 144 68 – – –
A/G 91 84 0.5116 (0.3383–0.7737) 1.49E−03a 7.78E−03b
G/G 15 22 0.322 (0.1572–0.6594) 1.95E−03a 7.78E−03b
Dominant A/A 144 68 0.4722 (0.3183–0.7006) 1.93E−04a 6.56E−04b
A/G-G/G 106 106
Recessive A/A-A/G 235 152 0.441 (0.2218–0.8768) 1.96E−02a 6.95E−02
G/G 15 22
Additive – – – 0.5441 (0.4003–0.7396) 1.02E−04a 3.25E−04b
SNP34 Codominant T/T 145 68 – – –
T/C 90 84 0.5025 (0.3321–0.7602) 1.12E−03a 7.78E−03b
C/C 15 22 0.3197 (0.1561–0.6548) 1.82E−03a 7.78E−03b
Dominant T/T 145 68 0.4645(0.313–0.6894) 1.41E−04a 6.43E−04b
T/C-C/C 105 106
Recessive T/T-T/C 235 152 0.441 (0.2218–0.8768) 1.96E−02a 6.95E−02
C/C 15 22
Additive – – – 0.5391 (0.3965–0.7328) 7.99E−05a 3.25E−04b
SNP35 Codominant C/C 145 68 – – –
C/G 90 83 0.5085 (0.3359–0.7698) 1.39E−03a 7.78E−03b
G/G 15 23 0.3058 (0.1502–0.623) 1.10E−03a 7.78E−03b
Dominant C/C 145 68 0.4645 (0.313–0.6894) 1.41E−04a 6.43E−04b
C/G-G/G 105 106
Recessive C/C-C/G 235 151 0.4191 (0.2119–0.8287) 1.24E−02a 6.95E−02
G/G 15 23
Additive – – – 0.5349 (0.394–0.7262) 6.06E−05a 3.25E−04b
SNP36 Codominant T/T 145 68 – – –
T/A 90 83 0.5085 (0.3359–0.7698) 1.39E−03a 7.78E−03b
A/A 15 23 0.3058 (0.1502–0.623) 1.10E−03a 7.78E−03b
Dominant T/T 145 68 0.4645 (0.313–0.6894) 1.41E−04a 6.43E−04b
T/A-A/A 105 106
Recessive T/T-T/A 235 151 0.4191 (0.2119–0.8287) 1.24E−02a 6.95E−02
A/A 15 23
Additive – – – 0.5349 (0.394–0.7262) 6.06E−05a 3.25E−04b
SNP39 Codominant A/A 144 68 – – –
A/G 91 84 0.5116 (0.3383–0.7737) 1.49E−03a 7.78E−03b
G/G 15 22 0.322 (0.1572–0.6594) 1.95E−03a 7.78E−03b
Dominant A/A 144 68 0.4722 (0.3183–0.7006) 1.93E−04a 6.56E−04b
A/G-G/G 106 106
Recessive A/A-A/G 235 152 0.441 (0.2218–0.8768) 1.96E−02a 6.95E−02
G/G 15 22
Additive – – – 0.5441 (0.4003–0.7396) 1.02E−04a 3.25E−04b
SNP41 Codominant C/C 162 81 – – –
C/T 76 80 0.475 (0.3146–0.7171) 3.97E−04a 2.16E−01
T/T 12 13 0.4615 (0.2015–1.057) 6.75E−02 2.16E−01
Dominant C/C 162 81 0.4731 (0.3187–0.7024) 2.05E−04a 6.56E−04b
C/T-T/T 88 93
Recessive C/C-C/T 238 161 0.6244 (0.2779–1.403) 2.54E−01 8.14E−01
T/T 12 13
Additive – – – 0.5659 (0.4094–0.7822) 5.65E−04a 1.51E−03b
SNP42 Codominant C/C 216 169 – – –
C/T 32 5 5.007 (1.91–13.13) 1.05E−03a 1.00E+00
T/T 1 0 1.264e+09 (0-inf) 9.99E−01 1.00E+00
Dominant C/C 216 169 5.164 (1.974–13.51) 8.22E−04a 2.19E−03b
C/T-T/T 33 5
Recessive C/C-C/T 248 174 1.133e+09 (0-inf) 9.99E−01 1.00E+00
T/T 1 0
Additive – – – 5.078 (1.953–13.21) 8.61E−04a 2.12E−03b
SNP45 Codominant T/T 145 68 – – –
T/C 90 84 0.5025 (0.3321–0.7602) 1.12E−03a 7.78E−03b
C/C 15 22 0.3197 (0.1561–0.6548) 1.82E−03a 7.78E−03b
Dominant T/T 145 68 0.4645 (0.313–0.6894) 1.41E−04a 6.43E−04b
T/C-C/C 105 106
Recessive T/T-T/C 235 152 0.441 (0.2218–0.8768) 1.96E−02a 6.95E−02
C/C 15 22
Additive – – – 0.5391 (0.3965–0.7328) 7.99E−05a 3.25E−04b
SNP46 Codominant G/G 218 169 – – –
G/A 31 5 4.806 (1.83–12.62) 1.44E−03a 1.00E+00
A/A 1 0 1.252e+09 (0-inf) 9.99E−01 1.00E+00
Dominant G/G 218 169 4.961 (1.893–13.01) 1.12E−03a 2.77E−03b
G/A-A/A 32 5
Recessive G/G-G/A 249 174 1.129e+09 (0-inf) 9.99E−01 1.00E+00
A/A 1 0
Additive – – – 4.879 (1.874–12.71) 1.17E−03a 2.67E−03b
SNP61 Codominant T/T 226 167 – – –
T/C 24 7 NA (NA–NA) NA 1.00E+00
C/C 0 0 NA (NA–NA) NA 1.00E+00
Dominant T/T 226 167 2.534 (1.066–6.019) 3.53E−02a 7.52E−02
T/C-C/C 24 7
Recessive T/T-T/C 250 174 NA (NA–NA) NA 1.00E+00
C/C 0 0
Additive – – – 2.534 (1.066–6.019) 3.53E−02a 7.52E−02
SNP69 Codominant A/A 80 82 – – –
A/G 124 80 1.589 (1.047–2.411) 2.96E−02a 4.65E−03b
G/G 46 12 3.929 (1.939–7.96) 1.45E−04a 4.65E−03b
Dominant A/A 80 82 1.894 (1.271–2.823) 1.71E−03a 3.90E−03b
A/G-G/G 170 92
Recessive A/A-A/G 204 162 3.044 (1.561–5.937) 1.09E−03a 3.49E−02b
G/G 46 12
Additive – – – 1.831 (1.354–2.476) 8.59E−05a 3.25E−04b

aIndicates that the data is statistically significant when before adjustment

bIndicates that the data is statistically significant when after FDR-BH correction