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. 2020 Apr 29;11(4):299. doi: 10.1038/s41419-020-2479-z

Fig. 5. Effects of CD9 and CD81 expression on the activity of JNK signaling pathway.

Fig. 5

a Cignal Finder Reporter Array was conducted in Huh7 cells transfected with CD9 or CD81 constructs. b, c Dual Luciferase reporter assays were performed using Huh7 (b) and HCC-LM3 (c) cells to determine whether CD9 or CD81 could affect the promoter activity of AP-1. d qPCR analyses were employed to determine whether CD9 or CD81 regulated Cyclin D1 and Bcl-2 mRNA expression level in Huh7 and HCC-LM3 cells. e Western blots were performed to verify the effects of altered CD9 or CD81 expression on the expression of specific proteins related with JNK signaling pathway. *P < 0.05, **P < 0.01.