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. 2020 Apr 29;10:7258. doi: 10.1038/s41598-020-64128-8

Table 2.

The expression levels of all significantly up- and downregulated proteins in glycolysis pathway for at least one of the three comparisons.

S.N. Uniprot Access. No. Protein Gene Name TurNP + EP vs Ctrl TurNP + EP vs EP TurNP + EP vs TurNP
Fold Change P Value Fold Change P Value Fold Change P Value
1 Q9BRR6 ADP-dependent glucokinase ADPGK 4.09# 1.1E-06* 4.09# 1.1E-06* 0.28 5.1E-02
2 P30837 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.82# 1.0E-03* 0.60# 1.4E-02* 0.77# 7.3E-04*
3 P05091 Aldehyde dehydrogenase, mitochondrial ALDH2 0.89# 3.1E-04* 0.71# 3.7E-03* 0.83# 3.7E-03*
4 P51648 Aldehyde dehydrogenase family 3 member A2 ALDH3A2 4.93# 2.4E-07* 4.93# 2.4E-07* 0.97# 9.7E-04*
5 P49189 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 5.28# 3.5E-07* 5.28# 3.5E-07* 0.36 1.3E-02*
6 Q86YI5 Acetyltransferase component of pyruvate dehydrogenase complex DLAT 0.87# 2.0E-04* 0.71# 3.2E-03* 1.10# 4.9E-05*
7 P19367 Hexokinase-1 HK1 0.65# 8.7E-02 0.76# 3.3E-03* 0.36 2.4E-02*
8 P52789 Hexokinase-2 HK2 4.87# 6.8E-03* 5.77# 3.0E-03* 3.07# 5.7E-03*
9 Q01813 ATP-dependent 6-phosphofructokinase, platelet type PFKP 1.17# 5.3E-03* 1.11# 3.5E-03* 0.75# 4.4E-03*
10 P08559 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial PDHA1 1.16# 1.9E-04* 1.26# 6.6E-04* 0.95# 6.3E-03*
11 P11177 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.70# 2.5E-03* 0.54# 1.5E-02* 0.76# 1.6E-03*
12 P09622 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.16 2.1E-01 0.03 7.5E-01 0.69# 4.7E-03*
13 P17858 ATP-dependent 6-phosphofructokinase, liver type PFKL 0.86# 1.8E-02* 0.61# 6.1E-02 3.69# 2.4E-02*
14 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial PCK2 0.67# 1.5E-03* 0.49 5.2E-02 2.21# 2.0E-01
15 P14550 Aldo-keto reductase family 1 member A1 AKR1A1 −4.16# 7.3E-05* 0.00 N/A -4.52# 2.2E-07*
16 P04075 Fructose-bisphosphate aldolase A ALDOA −1.87# 5.3E-03* −1.70# 5.4E-04* −1.68# 4.9E-04*
17 P09972 Fructose-bisphosphate aldolase C ALDOC −1.44# 3.7E-01 0.00 N/A −4.44# 6.9E-07*
18 P06733 Alpha-enolase ENO1 −1.68# 4.8E-03* −1.08# 1.4E-03* −1.67# 7.4E-05*
19 P09104 Gamma-enolase ENO2 −5.18# 3.7E-05* −3.65# 1.2E-01 −4.63# 4.3E-06*
20 P04406 Glyceraldehyde-3-phosphate dehydrogenase GAPDH −0.73# 5.7E-02 −0.34 2.2E-02* −0.51# 1.0E-03*
21 P00338 Lactate dehydrogenase A chain LDHA −0.79# 8.3E-03* −0.15 2.8E-01 −1.07# 4.6E-04*
22 P07195 Lactate dehydrogenase B chain LDHB −1.55# 1.8E-03* −1.19# 2.0E-03* −1.49# 2.7E-04*
23 P36871 Phosphoglucomutase-1 PGM1 −2.10# 7.9E-03* −1.52# 9.1E-03* −2.06# 3.5E-03*
24 P00558 Phosphoglycerate kinase 1 PGK1 −0.91# 5.7E-02 −0.35 3.5E-02* −0.96# 1.2E-03*
25 P18669 Phosphoglycerate mutase 1 PGAM1 −1.91# 1.1E-02* −1.57# 1.1E-02* −1.84# 6.0E-03*
26 P60174 Triosephosphate isomerase TPI1 −2.17# 6.5E-03* −2.05# 4.3E-03* −1.87# 3.3E-03*

The proteins with fold change indicated with #(|fold change | ≥0.5) and P value with *(P < 0.05) only are significantly regulated for a comparison.