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. 2020 Apr 23;11:609. doi: 10.3389/fmicb.2020.00609

FIGURE 3.

FIGURE 3

Virus-like particle immunization induces cell-mediated immune response in mice. Splenocytes from mice were stimulated with inactivated PPRV 2 weeks after the third immunization. Splenocytes producing IL-2 (A), IL-4 (B), IL-10 (C), or IFN-γ (D) were identified by ELISpot. Data are depicted as the means ± SD of SFCs per million splenocytes from three mice in each group and were analyzed by one-way ANOVA (*P < 0.05, **P < 0.01, ***P < 0.001).