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. 2020 Apr 23;10:443. doi: 10.3389/fonc.2020.00443

Figure 1.

Figure 1

Cytomorphology of bone marrow aspirates (A–C depict an overview of the slide; D–F show the cells at greater magnification; objective 63x). (A,D) Show a hypoplastic bone marrow after stem cell transplantation with up to 10% myeloblasts (marked by an arrow) resembling early relapse after allo-HSCT. Leukemic blasts display a basophilic cytoplasm frequently containing vacuoles. (B,E) (after one cycle of AZA) demonstrate a hypercellular marrow with ~50% of the previously described leukemic blasts (progressive disease). (C,F) (after two cycles of APA) show a normocellular marrow with an increased and left-shifted erythropoiesis, differentiated neutrophils and no evidence of an increased percentage of myeloblasts resembling complete remission.