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. 2020 Apr 23;10:522. doi: 10.3389/fonc.2020.00522

Table 1.

Baseline patient characteristics.

Maintenance therapy regimen
Variable Cetuximab Bevacizumab All
n = 79 (55.2%) n = 64 (44.8%) P-value n = 143 (100%)
Gender 0.24
   Female 27 (34.2%) 28 (43.8%) 55(38.5%)
   Male 52 (65.8%) 36 (56.3%) 88 (61.5%)
Age at maintenance, median (range) 62.0 (21.0–90.0) 61.0 (24.0–76.0) 0.70 62.0 (21.0–90.0)
Smoking 0.21
   Yes 34 (43.0%) 21 (32.8%) 55 (38.5%)
   No 45 (57.0%) 43 (67.2%) 88 (61.5%)
Primary tumor site 0.01
   Right colon 11 (13.9%) 24 (37.5%) 35 (24.5%)
   Left colon 68 (86.1%) 40 (62.5%) 108 (75.5%)
Number of metastatic sites at start of maintenance therapy 0.16
   0 0 (0.0%) 2 (3.1%) 2 (1.4%)
   1 35 (44.3%) 18 (28.1%) 53 (37.1%)
   2 28 (35.4%) 25 (39.1%) 53 (37.1%)
   ≥3 14 (17.7%) 16 (25.0%) 30 (21.0%)
   Unknown 2 (2.5%) 3 (4.7%) 5 (3.5%)
Metastatic time 0.49
   Synchronous 51 (64.6%) 39 (60.9%) 90 (62.9%)
   Metachronous 26 (32.9%) 25 (39.1%) 51 (35.7%)
   Unknown 2 (2.5%) 0 (0.0%) 2 (1.4%)
Preoperative chemotherapy 0.10
   Yes 20 (25.3%) 9 (14.1%) 29 (20.3%)
   No 59 (74.7%) 55 (85.9%) 114 (79.7%)
Surgical resection of primary tumor 0.16
   Yes 59 (74.7%) 54 (84.4%) 113 (79.0%)
   No 20 (25.3%) 10 (15.6%) 30 (21.0%)
Surgical resection of metastatic sites 0.83
   Yes 26 (32.9%) 20 (31.3%) 46 (32.2%)
   No 53 (67.1%) 44 (68.8%) 97 (67.8%)
Simultaneous resection 0.80
   Yes 10 (12.7%) 10 (15.6%) 20 (14.0%)
   No 68 (86.1%) 54 (84.4%) 122 (85.3%)
   Unknown 1 (1.3%) 0 (0.0%) 1 (0.7%)
Line of maintenance therapy initiated 0.68
   1 34 (43.0%) 23 (35.9%) 57 (39.9%)
   2 31 (39.2%) 29 (45.3%) 60 (42.0%)
   ≥3 14 (17.7%) 12 (18.8%) 26 (18.1%)

simultaneous resection refers to whether metastases and primary tumor site are simultaneously resected.