Table 3.
Concurrent criterion validity - Relationships between DSRS and clinical and radiological assessments at a variety of timepoints in trials of pharyngeal electrical stimulation. (Spearman’s rank correlation coefficient).
| DSRS* | Measure | Outcome | Range of Values | Timing (weeks) | N | Median (IQR) | rs | P |
|---|---|---|---|---|---|---|---|---|
| STEPS9 | ||||||||
| Total score | DSRS | Dysphagia | 0 to 12 | 0 | 154 | 7 (8) | — | — |
| 2 | 131 | 4 (5) | — | — | ||||
| 13 | 106 | 1 (3) | — | — | ||||
| VFS-PAS | Aspiration | 1 to 8 | 0 | 154 | 4.71 (3.66) | 0.488 | <0.001 | |
| 2 | 126 | 3.27 (3) | 0.387 | <0.001 | ||||
| 13 | 95 | 2.29 (2.93) | 0.398 | <0.001 | ||||
| TOR-BSST | Swallowing | 0 to 14 | 0 | 154 | 1 (3) | −0.167 | 0.038 | |
| 2 | 127 | 2 (10) | −0.459 | <0.001 | ||||
| 13 | 103 | 6 (13) | −0.520 | <0.001 | ||||
| NIHSS | Impairment | 0 to 42 | 0 | 150 | 9 (10) | 0.020 | 0.81 | |
| 2 | 131 | 8 (10) | 0.301 | <0.001 | ||||
| 13 | 106 | 5 (8) | 0.117 | 0.23 | ||||
| BI | Disability | 0 to 100 | 0 | 151 | 20 (40) | −0.279 | 0.001 | |
| 2 | 131 | 25 (60) | −0.517 | <0.001 | ||||
| 13 | 106 | 65 (65) | −0.407 | <0.001 | ||||
| mRS | Dependency | 0 to 5 | 0 | 151 | 4 (1) | 0.179 | 0.028 | |
| 2 | 131 | 4 (2) | 0.382 | <0.001 | ||||
| 13 | 106 | 4 (2) | 0.279 | 0.004 | ||||
| EQ-VAS | QoL | 0 to 100 | 13 | 87 | 58 (35) | −0.149 | 0.17 | |
| EQ-5D-3L | QoL | −0.5 to 1.0 | 13 | 95 | −0.04 (0.489) | −0.109 | 0.29 | |
| Fluids | VFS-PAS | Aspiration | 1 to 8 | 0 | 154 | 4.71 (3.66) | 0.498 | <0.001 |
| 2 | 126 | 3.27 (3) | 0.374 | <0.001 | ||||
| 13 | 95 | 2.29 (2.93) | 0.362 | <0.001 | ||||
| Diet | 0 | 154 | 4.71 (3.66) | 0.402 | <0.001 | |||
| 2 | 126 | 3.27 (3) | 0.416 | <0.001 | ||||
| 13 | 95 | 2.29 (2.93) | 0.371 | <0.001 | ||||
| Supervision | 0 | 154 | 4.71 (3.66) | 0.417 | <0.001 | |||
| 2 | 126 | 3.27 (3) | 0.236 | 0.008 | ||||
| 13 | 95 | 2.29 (2.93) | 0.343 | 0.001 | ||||
| Jayasekeran5 | ||||||||
| Total score | DSRS | Dysphagia | 0 to 12 | 0 | 28 | 5.5 (11) | — | — |
| 2 | 28 | 2.5 (5) | — | — | ||||
| VFS-PAS | Aspiration | 1 to 8 | 0 | 28 | 4.5 (3) | 0.345 | 0.073 | |
| 2 | 28 | 4 (3) | 0.146 | 0.46 | ||||
| BI | Disability | 0 to 20 | 0 | 28 | 6 (4) | −0.340 | 0.077 | |
| 2 | 28 | 14 (7) | −0.273 | 0.16 | ||||
| Vasant8 | ||||||||
| Total score | DSRS | Dysphagia | 0 to 12 | 0 | 36 | 8 (8) | — | — |
| 2 | 34 | 3 (8) | — | — | ||||
| 13 | 32 | 1 (3) | — | — | ||||
| VFS-PAS | Aspiration | 1 to 8 | 0 | 18 | 3.50 (4) | 0.551 | 0.018 | |
| 2 | 15 | 3 (2) | 0.537 | 0.039 | ||||
| 13 | 10 | 1 (2) | 0.159 | 0.66 | ||||
| NIHSS | Impairment | 0 to 42 | 0 | 36 | 11.50 (11) | 0.142 | 0.41 | |
| 2 | 33 | 6 (7) | 0.378 | 0.030 | ||||
| 13 | 26 | 4 (5) | 0.301 | 0.14 | ||||
| BI | Disability | 0 to 100 | 0 | 36 | 21.50 (39) | −0.017 | 0.92 | |
| 2 | 34 | 37.50 (50) | −0.400 | 0.019 | ||||
| 13 | 27 | 65 (58) | −0.258 | 0.20 | ||||
| mRS | Dependency | 0 to 5 | 0 | 35 | 4 (1) | −0.030 | 0.86 | |
| 2 | 33 | 3 (2) | 0.359 | 0.040 | ||||
| 13 | 27 | 2 (2) | 0.311 | 0.11 | ||||
| PHAST-TRAC10 | ||||||||
| Total score | DSRS | Dysphagia | 0 to 12 | 0 | 69 | 12 (0) | — | — |
| 0.3 | 60 | 10.5 (2.5) | — | — | ||||
| 13 | 52 | 5.1 (5.2) | — | — | ||||
| FOIS | Dysphagia | 1 to 7 | 0 | 69 | 1 (0) | ND | ND | |
| 0.3 | 60 | 1.8 (1.3) | −0.955 | <0.001 | ||||
| 13 | 52 | 4.3 (2.6) | −0.978 | <0.001 | ||||
*DSRS range is 0–12 for total score, and 0–4 for subscales.
BI: Barthel index; DSRS: dysphagia severity Rating scale; EQ-5D-3L/HUS: EuroQoL-5 dimension-3 level as health utility scale; EQ-VAS: EuroQoL-visual analogue scale; FOIS: functional oral intake scale; mRS: modified Rankin scale; NIHSS: National Institutes of Health Stroke Scale; PAS: penetration aspiration scale3; Richmond agitation and sedation scale (RASS)29; VFS: videofluoroscopy.
ND: Not done - all participants had DSRS = 12 and FOIS = 1 at baseline27.