Table 1.
Baseline characteristics across quartiles of red cell distribution width.
| MDCS (n = 27260) |
Quartile 1 (n = 6877) |
Quartile 2 (n = 6946) |
Quartile 3 (n = 6847) |
Quartile 4 (n = 6590) |
P |
|---|---|---|---|---|---|
| RDW range | 28.1–38.4 | 38.5–40.4 | 40.5–42.7 | 42.8–72.9 | |
| Age(years) | 56.9 ± 6.9 | 58.0 ± 7.5 | 58.6 ± 7.9 | 59.2 ± 8 | <0.001 |
| Sex(n,%) | <0.001 | ||||
| Male | 3049(44.3) | 2722(39.2) | 2488(36.3) | 2439(37.0) | |
| Female | 3828(55.7) | 4224(60.8) | 4359(63.7) | 4151(63.0) | |
| Smokers(n,%) | <0.001 | ||||
| Regularly | 719(10.5) | 1181(17.0) | 1750(25.6) | 2810(42.6) | |
| Occasionally | 282(4.1) | 325(4.7) | 306(4.5) | 317(4.8) | |
| Formerly | 2691(39.1) | 2519(36.3) | 2269(33.1) | 1742(26.4) | |
| Never | 3185(46.3) | 2921(42.1) | 2522(36.8) | 1721(26.1) | |
| History of diabetes(n,%) | 447(6.5) | 309(4.4) | 209(3.1) | 217(3.3) | <0.001 |
| History of CHD(n,%) | 113(1.6) | 134(1.9) | 125(1.8) | 145(2.2) | 0.036 |
| Anti-hypertensive medication(n,%) | 1287(18.7) | 1253(18.0) | 1190(17.4) | 1156(17.5) | 0.044 |
| Anti-lipid medication(n,%) | 232(3.4) | 208(3.0) | 212(3.1) | 186(2.8) | 0.100 |
| Anemia(n,%) | 218(3.2) | 186(2.7) | 185(2.7) | 224(3.4) | 0.465 |
| Waist circumference(cm) | 85.7 ± 12.7 | 84.6 ± 15.8 | 83.4 ± 12.7 | 82.7 ± 16.3 | <0.001 |
| Systolic blood pressure(mmHg) | 141.5 ± 19.6 | 141.1 ± 20 | 141.1 ± 20.2 | 141 ± 20.2 | 0.129 |
| Diastolic blood pressure(mmHg) | 86.4 ± 9.8 | 85.6 ± 9.9 | 85.3 ± 10.0 | 84.9 ± 10.0 | <0.001 |
| ApoA1(mg/dL) | 149.0(134.0,167.0) | 153.0(137.0,172.0) | 155.0(139.0,175.0) | 159.0(140.0,179.0) | <0.001 |
| ApoB(mg/dL) | 107.0(91.0,125.0) | 106.0(89.0,123.0) | 105.0(88.0,123.0) | 103.0(87.0,120.0) | <0.001 |
| ApoB/ApoA ratio | 0.72(0.58,0.87) | 0.69(0.55,0.84) | 0.67(0.54,0.83) | 0.65(0.52,0.79) | <0.001 |
| Total leukocyte count(109/L) | 5.8(5.0,6.9) | 6.0(5.1,7.1) | 6.3(5.3,7.4) | 6.5(5.4,7.7) | <0.001 |
| Neutrophil count (109/L) | 3.5(2.9,4.3) | 3.6(3.0,4.5) | 3.8(3.0,4.6) | 3.9(3.1,4.9) | <0.001 |
| Lymphocyte count(109/L) | 1.8(1.5,2.2) | 1.9(1.5,2.2) | 1.9(1.5,2.3) | 1.9(1.6,2.4) | <0.001 |
| Neutrophil/ Lymphocyte ratio | 1.94(1.54,2.47) | 1.95(1.55,2.48) | 2.0(1.6,2.5) | 2.0(1.6,2.6) | <0.001 |
| MCV(fL) | 86.1 ± 3.4 | 88.2 ± 2.9 | 90.2 ± 3 | 93.2 ± 3.6 | <0.001 |
| Hemoglobin(g/dL) | 142.6 ± 12.2 | 141.7 ± 11.9 | 141.3 ± 11.7 | 141.3 ± 12.1 | <0.001 |
Continuous variables were shown as mean (SD) or median (Q25,Q75); Categorical variables were shown as number (%).