Table 2.
Adjusted hazard ratios for AAA.
| RDW | Person years | Incident | Crude HR (95%CI) |
Model 1 HR(95%CI) |
Model 2 HR(95%CI) |
Model 3 HR(95%CI) |
|---|---|---|---|---|---|---|
| Total AAA | ||||||
| Quartile 1 | 142437 | 83 | Ref | Ref | Ref | Ref |
| Quartile 2 | 139988 | 111 | 1.38(1.04,1.83) | 1.39(1.05,1.85) | 1.21(0.91,1.61) | 1.23(0.92,1.64) |
| Quartile 3 | 134628 | 131 | 1.71(1.30,2.26) | 1.75(1.33,2.31) | 1.38(1.04,1.83) | 1.40(1.06,1.86) |
| Quartile 4 | 122294 | 166 | 2.46(1.89,3.20) | 2.45(1.88,3.20) | 1.58(1.19,2.09) | 1.61(1.20,2.12) |
| P for trend | <0.001 | <0.001 | 0.001 | 0.001 | ||
| Surgically treated or ruptured AAA | ||||||
| Quartile 1 | 142437 | 37 | Ref | Ref | Ref | Ref |
| Quartile 2 | 139988 | 55 | 1.52(1.00,2.31) | 1.58(1.04,2.40) | 1.33(0.87,2.02) | 1.35(0.89,2.06) |
| Quartile 3 | 134628 | 53 | 1.53(1.01,2.33) | 1.64(1.07,2.51) | 1.22(0.79,1.88) | 1.24(0.81,1.91) |
| Quartile 4 | 122294 | 76 | 2.46(1.66,3.65) | 2.59(1.74,3.87) | 1.57(1.03,2.39) | 1.58(1.04,2.41) |
| P for trend | <0.001 | <0.001 | 0.062 | 0.059 | ||
| Non-surgically treated and non-ruptured AAA | ||||||
| Quartile 1 | 142437 | 46 | Ref | Ref | Ref | Ref |
| Quartile 2 | 139988 | 56 | 1.26(0.86,1.87) | 1.25(0.84,1.85) | 1.11(0.75,1.65) | 1.13(0.76,1.67) |
| Quartile 3 | 134628 | 78 | 1.86(1.29,2.68) | 1.84(1.27,2.65) | 1.52(1.04,2.21) | 1.54(1.06,2.24) |
| Quartile 4 | 122294 | 90 | 2.45(1.72,3.49) | 2.35(1.64,3.37) | 1.59(1.08,2.32) | 1.60(1.09,2.35) |
| P for trend | <0.001 | <0.001 | 0.006 | 0.005 | ||
Model 1: age, sex adjusted.
Model 2: Model 1 + smoking + diabetes + CHD + waist circumference + systolic blood pressure + ApoB/ApoA1 ratio + WBC + hemoglobin + MCV (classified by <80fl, 80–100fl and >100fl).
Model 3: Model 2 + anti-hypertension medications + lipid-lowing medication.