Table 2.

Chemical shifts discriminating between TB and other diseases in Gambian children at enrolment. Peaks without significant variables on either side were ignored.

	1H ppm	Carbon ppm	r (CI lower and upper bound)	P value	Q value FDR	Increased in	1H NMR peak multiplicity	Potential metabolite
1	1.427	19.07	0.36 (0.26–0.44)	<0.001	0.03	TB	Doublet	Unknown
2	1.498	19	−0.38 (−0.47– −0.29)	<0.001	0.02	Other diseases	Doublet	Alanine
3	2.044	29.68	0.36 (0.24–0.45)	<0.001	0.03	TB	Multiplet	Glutamate
4	2.054	24.83	0.50 (0.40–0.58)	<0.001	0.004	TB	Broad resonance	N-acetyl glycoprotein (Glyc-A)
5	2.076		0.41 (0.30–0.50)	<0.001	0.01	TB	Broad resonance	O-acetyl glycoprotein
6	2.106	25.14	0.45 (0.36–0.53)	<0.001	0.01	TB	Multiplet	Glutamate
7	2.159		0.36 (0.25–0.44)	<0.001	0.03	TB	Multiplet	Glutamate
8	2.489		−0.37 (−0.50– −0.24)	<0.001	0.02	Other diseases	Triplet	Unknown
9	2.549		−0.41 (−0.51–−0.30)	<0.001	0.01	Other diseases	Doublet	Unknown
10	2.715		0.38 (0.27–0.48)	<0.001	0.02	TB	Multiplet	Glutamate
11	2.931		−0.44 (−0.53–−0.35)	<0.001	0.01	Other diseases	Broad resonance	Unknown
12	2.963		−0.42 (−0.51– −0.33)	<0.001	0.01	Other diseases	Broad resonance	Unknown
13	3.258		−0.41 (−0.51– −0.29)	<0.001	0.01	Other diseases	Undetermined	Unknown
14	3.601		0.44 (0.35–0.52)	<0.001	0.01	TB	Undetermined	Unknown
15	3.629		0.36 (0.26–0.44)	<0.001	0.03	TB	Undetermined	Unknown
16	3.642		0.37 (0.27–0.46)	<0.001	0.02	TB	Undetermined	Unknown
17	3.664		0.38 (0.26–0.48)	<0.001	0.02	TB	Undetermined	Unknown
18	3.685		0.39 (0.28–0.50)	<0.001	0.01	TB	Undetermined	Unknown
19	3.692		0.39 (0.29–0.48)	<0.001	0.01	TB	Doublet of doublets	Unknown
20	3.702		0.40 (0.29–0.49)	<0.001	0.01	TB	Doublet of doublets	Glyc-A
21	3.707		0.40 (0.29–0.49)	<0.001	0.01	TB	Singlet	Leucine
22	3.900	68.94	0.43 (0.34–0.52)	<0.001	0.01	TB	Undetermined	Unknown
23	3.925		0.42 (0.32–0.51)	<0.001	0.01	TB	Undetermined	Glyc-A
24	7.342		0.35 (0.22–0.46)	<0.001	0.03	TB	Doublet	Phenylalanine