Table 2.
Cox univariate and multivariate analysis of predictors of overall survival following hepatectomy.
| Variables for overall survival | Univariate analysis | p-value | Multivariate analysis | p-value |
|---|---|---|---|---|
| HR (95% CI) | HR (95%CI) | |||
| Age, year (>50 versus ≤50) | 1.330 (0.640–2.762) | 0.444 | ||
| Gender (male versus female) | 3.157 (0.430–23.193) | 0.258 | ||
| HBsAg (positive versus negative) | 0.918 (0.375–2.247) | 0.852 | ||
| Cirrhosis (present versus absent) | 1.754 (0.418–7.365) | 0.443 | ||
| Tumor encapsulation (complete/no) | 2.041 (0.955–4.364) | 0.066 | 2.195 (1.024–4.707) | 0.043 |
| Tumor size, cm (>5 versus ≤5) | 1.985 (0.963–4.089) | 0.063 | 2.217 (1.070–4.592) | 0.032 |
| Tumor number (multiple versus single) | 1.659 (0.634–4.342) | 0.302 | ||
| Edmondson–Steiner grade (I–II / III–IV) | 2.073 (0.998–4.306) | 0.051 | NA | NA |
| Vascular invasion (yes versus no) | 2.167 (1.051–4.467) | 0.036 | NA | NA |
| Preoperative AFP level, ng/ml (>400 versus ≤400) | 1.120 (0.533–2.354) | 0.765 | ||
| TNM stage (I/II–III) | 1.707 (0.832–3.500) | 0.144 | ||
| ACSL4 expression (high versus low) | 2.136 (1.016–4.492) | 0.045 | 2.434 (1.149–5.153) | 0.020 |
AFP alpha-fetoprotein, HR hazard ratio, 95% CI 95% confidence interval.