Table 4.
Amount of concentrated amplified nuclear DNA in miPGT-1 (WGA with cell lysis) and miPGT-2 (WGA without cell lysis) samples.
| Types of samples | Amplification rate (%) | WGA-DNA range (ng/µl) | WGA-DNA concentration (ng/µl) | Informative NGS results (%) |
|---|---|---|---|---|
| miPGT-1 (with cell lysis) | 43/43 (100) | 6.3 to 85.9 | 37.3 ± 19.4* | 40/43 (93.0)* |
| miPGT-2 (without cell lysis) | 43/43 (100) | 10.2 to 72.7 | 32.8 ± 16.3* | 38/43 (88.4)* |
| miPGT, total | 86/86 (100) | 6.3 to 85.9 | 35.05 ± 17.85 | 78/86 (90.7) |
| TE biopsy** | 43/43 (100) | 32.3 to 52.4 | 43.2 ± 3.5 | 41/43 (95.3)* |
*Not statistically significant Difference between the values in the same column.
**Not concentrated amplified DNA in TE biopsy sample.