Table 2.
Contingency table of a Chi-square test of genes with polymorphisms in miRNA binding sites located within QTL. Testing for an enrichment of genes with metabolically relevant phenotypes of knockout mice according to the IMPC (A) and MGI databases (B). Numbers describe observed occurrence, numbers in brackets indicate expectations if the hits would be random.
| Filtered | Others | Marginal Row Totals | |
|---|---|---|---|
| a | |||
| Other phenotype | 13 (17) | 5102 (5098) | 5115 |
| Metabolic phenotype | 8 (4) | 1116 (1120) | 1124 |
| Marginal Column Totals | 21 | 6218 | 6239 (Grand Total) |
| P-value: | 0.016 | ||
| Odds ratio: | 2.81 | ||
| b | |||
| Other phenotype | 18 (22) | 14461 (14457) | 14479 |
| Metabolic phenotype | 7 (3) | 1738 (1742) | 1745 |
| Marginal Column Totals | 25 | 16199 | 16224 (Grand Total) |
| P-value: | 0.005 | ||
| Odds ratio: | 3.24 | ||