Table 2.
Cognitive profiles of Alzheimer’s disease subtype.
| Rt-AD (n = 32) | Sym-AD (n = 173) | Lt-AD (n = 38) | p | |||
|---|---|---|---|---|---|---|
| Rt-AD vs Sym-AD | Rt-AD vs Lt-AD | Sym-AD vs Lt-AD | ||||
| Attention | ||||||
| Backward digit span | −1.6 ± 1.4 | −1.1 ± 1.4 | −1.3 ± 1.0 | 0.517 | 1.000 | 1.000 |
| Letter cancellation, abnormal | 7 (22%) | 26 (15%) | 7 (18%) | 1.000 | 1.000 | 1.000 |
| Language | ||||||
| K-BNT | −2.9 ± 2.7 | −2.5 ± 2.1 | −5.1 ± 4.3 | 0.825 | 0.089 | 0.002 |
| Calculation, abnormal | 23 (72%) | 101 (62%) | 32 (84%) | 0.968 | 0.754 | 0.024 |
| Visuospatial function | ||||||
| RCFT: copying | −8.2 ± 6.7 | −4.6 ± 5.6 | −4.3 ± 5.3 | 0.013 | 0.052 | 1.000 |
| Memory | ||||||
| SVLT: delayed recall | −2.8 ± 0.8 | −2.8 ± 1.1 | −2.6 ± 0.8 | 0.927 | 0.186 | 0.926 |
| RCFT: delayed recall | −2.6 ± 0.6 | −2.3 ± 0.8 | −2.1 ± 0.9 | 0.032 | 0.008 | 0.389 |
| Frontal/executive functions | ||||||
| COWAT animal | −2.0 ± 1.2 | −1.7 ± 1.0 | −2.5 ± 1.4 | 0.559 | 0.235 | 0.004 |
| COWAT phonemic | −1.4 ± 1.2 | −1.2 ± 1.1 | −1.8 ± 1.1 | 1.000 | 0.874 | 0.113 |
| Stroop test: color | −3.2 ± 2.2 | −3.0 ± 2.0 | −3.4 ± 1.6 | 1.000 | 1.000 | 0.724 |
| MMSE | −8.2 ± 5.0 | −5.6 ± 3.9 | −8.8 ± 4.7 | 0.015 | 1.000 | 0.001 |
| CDR | 1.2 ± 0.8 | 1.0 ± 0.5 | 1.0 ± 0.5 | 0.898 | 1.000 | 1.000 |
| GDepS | 5.1 ± 4.5 | 4.0 ± 3.4 | 2.4 ± 2.3 | 1.000 | 1.000 | 1.000 |
AD, Alzheimer’s disease; CDR, Clinical Dementia Rating; COWAT, Controlled Oral Word Association Test; GDepS, Geriatric Depression Score; K-BNT, Korean version of the Boston Naming Test; lvPPA, logopenic variant primary progressive aphasia; RCFT, Rey-Osterrieth complex figure test; Rt-AD, AD with right focal atrophy; SVLT, Seoul verbal learning test; Sym-AD, AD with symmetric atrophy; MMSE, Mini-mental State Examination.